
At RHMD in Beverly Hills, skin rejuvenation is approached through a regenerative lens that prioritizes cellular health, longevity, and biological function. Led by Dr. Raffi Hovsepian, MD, a triple board-certified plastic surgeon and regenerative medicine specialist, our practice integrates aesthetic precision with evidence-based therapies designed to support how skin repairs, communicates, and evolves over time. Rather than focusing solely on surface correction, RHMD addresses the underlying processes that influence skin quality, which is where peptides play a critical role. Let’s take a closer look at what peptides actually do for your skin and why they have become central to advanced regenerative aesthetics.
What Peptides Are and Why They Matter for Skin Health
Peptides are short chains of amino acids, some of which act as signaling molecules that influence how cells communicate and respond to various stimuli. In the skin, certain peptides have been shown to influence processes such as collagen signaling, inflammatory response modulation, barrier support, and aspects of tissue repair. When peptide signaling is efficient, skin maintains structure, elasticity, and the ability to recover from daily stressors.
With age, these signaling pathways become less efficient. Collagen synthesis slows, inflammation becomes more persistent, and recovery from sun exposure, procedures, or environmental damage takes longer. This gradual breakdown in communication contributes to visible changes such as thinning skin, uneven texture, loss of firmness, and a dull appearance.
How Peptides Influence Visible Skin Rejuvenation
In skin-focused applications, peptides are primarily discussed for how they may support visible improvements over time by influencing surface-adjacent biological processes. Rather than acting as instant correctives, certain peptides are formulated to support the skin’s own maintenance systems, which can contribute to gradual improvements in texture, firmness, and resilience.
Depending on the peptide type and delivery method, their skin-related roles may include:
- Collagen signaling support: Helps influence fibroblast activity involved in maintaining collagen and elastin structure.
- Inflammation modulation: Assists in regulating low-grade inflammation that contributes to redness, sensitivity, and accelerated aging.
- Barrier reinforcement: Supports the skin’s protective barrier, improving hydration retention and tolerance to environmental stress.
- Recovery support: May aid the skin’s natural recovery processes following procedures or environmental exposure.
These effects are generally subtle and cumulative, making peptides best suited for long-term skin quality support rather than immediate transformation.
Clinical Peptides and Regenerative Skin Support
In a clinical or regenerative context, peptides are approached differently than topical skincare ingredients. Rather than targeting surface appearance alone, certain physician-guided peptide therapies are used to support broader biological functions that can indirectly influence skin health, recovery, and resilience.
At RHMD, this regenerative approach may include:
- BPC-157: A therapeutic peptide studied for its role in supporting tissue repair and inflammatory regulation, which may be beneficial in recovery-focused treatment plans.
- NAD+: A vital coenzyme involved in cellular energy production and oxidative stress regulation, often incorporated to support overall cellular function and resilience.
These therapies are not designed as direct skin rejuvenation treatments. Instead, they may be considered as part of a comprehensive regenerative strategy that supports the physiological environment in which skin repair and maintenance occur.
Why Personalization Is Essential in Peptide Therapy
Peptide therapy is not one-size-fits-all. Different skin concerns require different signaling support, whether the focus is aging, inflammation, recovery, or overall vitality. At RHMD, peptide-based plans begin with a comprehensive consultation that considers skin condition, medical history, lifestyle factors, and aesthetic goals.
Under the direction of Dr. Hovsepian, peptide protocols are selected and monitored with precision, ensuring that skin-focused benefits align with whole-body wellness and sustainable outcomes rather than temporary cosmetic effects.
The Bottom Line on Peptides and Your Skin
Peptides are often labeled as skincare buzzwords, but their real value lies in supporting cellular communication, recovery, and long-term skin function. Used appropriately, they can help reinforce the biological signals that allow skin to remain resilient and age more gradually. Dr. Hovsepian applies a regenerative-focused approach to carefully selected, personalized care. To explore whether peptide-based strategies may support your skin goals, schedule a consultation with RHMD today.